Well, that’s a good question! The most obvious one is in the name: co-browsing is browser based, meaning that you only share the browser instead of sharing your entire screen (which is the case with screen sharing). 

Less obvious is that both technologies come with their own approaches. Co-browsing solutions usually make use of a Javascript approach, which means that the HTML, Javascript and CSS of a website are synchronized between users. This allows you to extend the online experience to multiple users, and therefore add a multi-user experience on your website.

Screen-sharing solutions are pixel-based, the drawback of this approach is that screen updates are slow and of low quality. What most screen-sharing tools have in common, is that they require external software to be installed by the users. This makes it unsuitable for most web situations as people are often unwilling to install extra software that circumvents the browser's security measures.

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